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The Future of Biomarkers in Veterinary Medicine: Emerging Approaches and Associated Challenges

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posted on 2025-05-09, 20:42 authored by Tharangani R. W. Perera, David Skerrett-ByrneDavid Skerrett-Byrne, Zamira GibbZamira Gibb, Brett NixonBrett Nixon, Aleona SwegenAleona Swegen
New biomarkers promise to transform veterinary practice through rapid diagnosis of diseases, effective monitoring of animal health and improved welfare and production efficiency. However, the road from biomarker discovery to translation is not always straightforward. This review focuses on molecular biomarkers under development in the veterinary field, introduces the emerging technological approaches transforming this space and the role of ‘omics platforms in novel biomarker discovery. The vast majority of veterinary biomarkers are at preliminary stages of development and not yet ready to be deployed into clinical translation. Hence, we examine the major challenges encountered in the process of biomarker development from discovery, through validation and translation to clinical practice, including the hurdles specific to veterinary practice and to each of the ‘omics platforms–transcriptomics, proteomics, lipidomics and metabolomics. Finally, recommendations are made for the planning and execution of biomarker studies with a view to assisting the success of novel biomarkers in reaching their full potential.

History

Journal title

Animals

Volume

12

Issue

17

Article number

2194

Publisher

MDPI AG

Language

  • en, English

College/Research Centre

College of Engineering, Science and Environment

School

School of Environmental and Life Sciences

Rights statement

© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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