This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effectiveness of universal, selective and indicated family-based prevention programs in preventing alcohol use, or problem drinking, in school-aged children (up to 18 years of age). Specifically, on these outcomes, the review aims: 1. To assess the effectiveness of universal family-based prevention programs for all children up to 18 years (‘universal interventions’). ; 2. To assess the effectiveness of selective family-based prevention programs for children up to 18 years at elevated risk of alcohol use or problem drinking (‘selective interventions’). 3. To assess the effectiveness of indicated family-based prevention programs for children up to 18 years currently consuming alcohol (‘indicated interventions’).