Differences in health-related quality of life between three clusters of physical activity, sitting time, depression, anxiety, and stress

Background: Physical inactivity, sitting behaviour, and mental health problems are detrimental to health-related quality of life but typically are considered as independent determinants. This study tested how these factors clustered together as profiles of subgroups of people and whether the clusters differed as a function of physical and mental health-related quality of life. Methods: In 2012, Australian adults (N =1,014) self-reported their physical and mental health-related quality of life, physical activity, sitting time, depression, anxiety, and stress using a web-based survey. Cluster analysis was used to identify subgroups of health behaviour and mental health profiles, and ANOVA was used to test for between-cluster differences in health-related quality of life. Results: Three subgroups were identified: people with higher psychological stress (n =13%), people with higher amounts of sitting time (n =45%), and people with lower amounts of sitting time (n =42%). There were no differences in mental health-related quality of life between subgroups; however people represented by the subgroup of higher amounts of sitting time had significantly lower physical health-related quality of life than the other two subgroups, F(2, 1011) =10.04, p < .01. Conclusions: Interventions should consider that (1) physical activity, sitting time, and psychological distress are aspects of multifaceted behavioural-psychological profiles, and (2) reductions of sitting time may have major impacts for physical health-related quality of life.