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A pharmacological approach to first aid treatment for snakebite

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posted on 2025-05-10, 09:01 authored by Megan E. Saul, Paul A. Thomas, Peter DosenPeter Dosen, Geoffrey IsbisterGeoffrey Isbister, Margaret A. O'Leary, Ian M. Whyte, Sally A. McFadden, Dirk Van HeldenDirk Van Helden
Snake venom toxins first transit the lymphatic system before entering the bloodstream. Ointment containing a nitric oxide donor, which impedes the intrinsic lymphatic pump, prolonged lymph transit time in rats and humans and also increased rat survival time after injection of venom. This pharmacological approach should give snakebite victims more time to obtain medical care and antivenom treatment.

History

Journal title

Nature Medicine

Volume

17

Issue

7

Pagination

809-811

Publisher

Nature Publishing Group

Language

  • en, English

College/Research Centre

Faculty of Health

School

School of Biomedical Sciences and Pharmacy

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