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A parallel modelling algorithm for simulating calcium release in cells

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conference contribution
posted on 2025-05-10, 12:45 authored by Jeremy G. Stoddard, James Welsh, Derek LaverDerek Laver
Using a spatially discretised model structure to represent the behaviour of calcium release sites in a cell, this paper presents a parallel solution algorithm which treats each release site as an independent sub-system, and manages inter-site data communication on a global timestep. When compared to the equivalent single-thread solution algorithm, the parallel method features a negligible reduction in accuracy, and improves computation time scaling from a quadratic, O(n²) to a linear, O(n), with respect to the number of release sites, n, in the model.

History

Source title

Proceedings of the 6th IFAC Conference on Foundations of Systems Biology in Engineering [presented in IFAC Papers Online, Vol. 49 No. 26]

Name of conference

6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE 2016)

Location

Magdeburg, Germany

Start date

2016-10-09

End date

2016-10-12

Pagination

83-88

Editors

Findeisen, R., et. al

Publisher

International Federation of Control (IFAC)

Place published

Laxenburg, Austria

Language

  • en, English

College/Research Centre

Faculty of Engineering and Built Environment

School

School of Electrical Engineering and Computer Science

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